CDC Clinical Guidance for 25-26 Influenza Season

Published: 01/02/2026

Sources:
  • Centers for Disease Control and Prevention
Relevant To:
  • Rural Emergency Hospitals,
  • Telehealth,
  • Urgent Care,
  • Medical Office,
  • Critical Access Hospitals,
  • Hospitals,
  • Long Term Care,
  • Clinical Lab,
  • Pharmacy,
  • Rural Health Clinics

The U.S. Centers for Disease Control and Prevention recently provided updated guidance for seasonal influenza prevention, diagnosis, and treatment for the 2025–2026 influenza season.

According to the CDC, the 2024–2025 influenza season was unusually severe, with high levels of hospitalization, mortality, and complications across age groups. Early surveillance data indicate that influenza activity is again increasing earlier in the 2025–2026 season, reinforcing the need for timely vaccination,

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