CDC’s ACIP Recommends Individual-Based Decision-Making for Hepatitis B Vaccine for Infants Born to Women Who Test Negative for the Virus

Published: 12/08/2025

Sources:
  • Centers for Medicare and Medicaid Services,
  • Centers for Disease Control and Prevention
Relevant To:
  • Rural Emergency Hospitals,
  • Telehealth,
  • Urgent Care,
  • Medical Office,
  • Critical Access Hospitals,
  • Hospitals,
  • Ambulatory Care,
  • Clinical Lab,
  • Rural Health Clinics

The U.S. Centers Disease Control and Prevention’s (CDC) Advisory Committee on Immunization Practices (ACIP) voted 8–3 to shift the longstanding universal recommendation for the hepatitis B birth dose to an individual-based (shared clinical) decision-making model for infants born to mothers who test negative for hepatitis B.

Under this new approach, parents and clinicians are advised to jointly determine whether to administer the birth dose or to start the hepatitis B vaccine series later. If …

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