Mpox in the United States - Situation Update

Published: 10/30/2025

Sources:
  • Centers for Disease Control and Prevention
Relevant To:
  • Medical Office,
  • Critical Access Hospitals,
  • Hospitals

The U.S. Centers for Disease Control and Prevention (CDC) recently updated the status of Mpox in the United States:

  • Health authorities in Southern California have reported three cases of clade 1 Mpox in people with no recent travel. All three individuals are recovering from the illness. The public health investigation is ongoing. For more information see Community Spread of Clade I Mpox Within California.
  • There have been six reported cases of clade I monkeypox in the United States in peo

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